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Another Strike Against Growth Hormone
(Thursday March 04 2010)
 | Something to think about from EurekAlert!: "IGF-I is a protein hormone similar in structure to insulin and is regulated in the body by growth hormone (GH). Levels of GH and IGF-I decline progressively with age in both men and women and this drop is thought to be related to deteriorating health conditions found with advanced age. In an attempt to combat aging some people use GH as its actions elevate IGF-1. This study however showed that older men who had higher levels of IGF-I were more likely to die from a cancer-related cause in the following 18 years than men with lower levels. ... This is the first population-based study to show an association of higher IGF-I levels with increased risk of a cancer-related death in older men. Although the design of this study does not explicitly show that the higher IGF-I levels caused the cancer death, it does encourage more study as well as a reexamination of the use of IGF-I enhancing therapies as an anti-aging strategy. ... researchers used data on 633 men aged 50 and older from the Rancho Bernardo Study, a population-based study of healthy aging. ... In this study, the increased risk of cancer death for older men with high levels of IGF-I was not explained by differences in age, body size, lifestyle or cancer history." You might compare this with other findings on IGF-1 levels in long-lived humans. |
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